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KMID : 1039420180520010045
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Journal of Pathology and Translational Medicine
2018 Volume.52 No. 1 p.45 ~ p.50
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Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma
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Han Kang-Hee
Ha Hwa-Jeong
Kong Joon-Seog
Myung Jae-Kyung
Park Sun-Hoo
Kim Jung-Soon
Shin Myung-Soon
Seol Hye-Sil
Koh Jae-Soo
Lee Seung-Sook
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Abstract
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Background: Although histological diagnosis of pilomatricoma is not difficult because of its unique histological features, cytological diagnosis through fine-needle aspiration cytology (FNAC) is often problematic due to misdiagnoses as malignancy.
Methods: We reviewed the cytological features of 14 cases of histologically-proven pilomatricoma from Korea Cancer Center Hospital, with a discussion on the diagnostic pitfalls of FNAC.
Results: Among 14 cases of pilomatricoma, 10 (71.4%) were correctly diagnosed through FNAC, and two (14.3%) were misdiagnosed as carcinoma. Cytologically, all cases had easily recognizable clusters of basaloid cells and foreign body-type multinucleated cells. Although ghost cells were also found in all cases, some were inconspicuous and hardly recognizable due to their small numbers.
Conclusions: An accurate diagnosis of pilomatricoma in FNAC is feasible with consideration of clinical information and close examination of ghost cells.
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KEYWORD
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Pilomatricoma, Fine-needle aspiration cytology, Ghost cells
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